The Extreme Nutritional Benefits of Mushrooms: Varieties and Mechanisms of Pro-Metabolic, Anti-Cancer, Anti-Death, Nootropic Effects

Mushrooms have been part of the human diet for up to 18,000 years, since the Upper Paleolithic's Magdalenian phase, possibly beginning with bolete (porcini) variety mushrooms, which are still popular in Italian cuisine today. Delicious and an ample quality-protein source, mushrooms are also extremely beneficial to health in important ways. Generally, they are nootropic brain-protectants, … Continue reading The Extreme Nutritional Benefits of Mushrooms: Varieties and Mechanisms of Pro-Metabolic, Anti-Cancer, Anti-Death, Nootropic Effects

Meat and Eggs are Health Foods. Ignore Technocratic Misanthropy.

Since early 2020, cardiovascular disease has killed almost twice the amount of people as the SARS-Cov-2 virus, and poor cardiovascular health increases the chance of mortality from that virus by 10.5%. Cardiovascular disease is the #1 cause of death globally, killing almost 20 million people per year, and rates and resultant mortality continue to rise. … Continue reading Meat and Eggs are Health Foods. Ignore Technocratic Misanthropy.

A Simple Science-Backed Caffeine Optimization Guide

Caffeine, as I have written about before, is the world's most popular plant drug. Some more enthusiastic about it even call it an adaptogen, or nutrient, while others point out that it acts as an insecticide and toxin. However complex its properties and potential uses, it is a permanent and ubiquitous part of the human … Continue reading A Simple Science-Backed Caffeine Optimization Guide

Resilience of the Bolivian Tsimané: High-Carb, Healthy Hearts, and Helminthic Mutualism

Indigenous peoples eat everything we’re told is bad for us, but they’re relatively free of modern disease; whether meat-based or fruit-based, they do much better than industrialized peoples. This is partially because they live in sunlight, avoid blue light, are very physically active, and have cyclic and diverse gut bacteria, even pathogens and parasites. A … Continue reading Resilience of the Bolivian Tsimané: High-Carb, Healthy Hearts, and Helminthic Mutualism

The Case for the Biological Superiority of Raw Milk: History, Mechanisms, and Current Conditions

Basic advantages of raw milk Raw milk’s probiotics, immunoglobulins, unique protein and fatty acid composition, and cytokines like transforming growth factor-beta-1 regulate and enhance development of the human immune system (Peroni, et al., 2009). Consumption of raw cow's milk reduces the risk of respiratory infections and fever by about 30% in children (Loss, et al., … Continue reading The Case for the Biological Superiority of Raw Milk: History, Mechanisms, and Current Conditions

Klotho & Intermittent Fasting: Brain, Adaptation, & Longevity

The Three Fates (c. 1910) by Alexander Rothaug Klotho is the “longevity gene”, named after the Greek Goddess of Fate who spins the threads of human life, determining when we live and die. Klotho regulates neurogenesis, calcium and phosphate excretion, blood vessels, fat storage, and insulin signaling, with other yet unknown functions. Mice who lack … Continue reading Klotho & Intermittent Fasting: Brain, Adaptation, & Longevity

Serotonin and the Kynurenine Problem

It's possible that Ray Peat’s classification of serotonin as primarily an inflammatory mediator is largely due to the tryptophan → kynurenine pathway that happens during inflammation, and everything bad that kynurenine metabolites do is almost all blamed on serotonin (Haq, et al., 2021). Problems with serotonin metabolism can largely be explained by activation of the … Continue reading Serotonin and the Kynurenine Problem

Clarifying the False Relationship of Cholesterol & Saturated Fat to Heart Disease

It is still extremely common to hear household and mainstream discussion about “reducing fatty foods” and “watching your cholesterol” by avoiding eggs and red meat and eating low-fat ultra-processed products even if they are loaded with added sugar, rancid oils, or toxic additives. The evidence for these measures isn’t good science, but the dogma of … Continue reading Clarifying the False Relationship of Cholesterol & Saturated Fat to Heart Disease

Best Ways to Treat Akathisia That Actually Might Work

Left: Diego Velazquez's Portrait of Pope Innocent X (1650), and, Right: Francis Bacon's Study After Velazquez's Portrait of Pope Innocent X (1953). Akathisia is a great example of the horrors of iatrogenic illness: illness, created by medical treatments, that has never existed before in human history. The fact that it is so much more excruciating … Continue reading Best Ways to Treat Akathisia That Actually Might Work

Why is Everyone so Sick & Fat? Sugar, Starch, Leaky Gut, & Dysbiosis

Sugar and starch, in the doses we eat that are normalized by the modern world, are poisons to the gut and the brain. Their effects are so destructive, and their use so addictive, that in the future they may rightfully be seen as recreational drugs. It is not that carbohydrates are simply “bad”. It is … Continue reading Why is Everyone so Sick & Fat? Sugar, Starch, Leaky Gut, & Dysbiosis